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Seventy - four - year - old Marilyn Butterfield shake off her leg when she sit down for dinner . She shakes her legs when she sits down to take , and she shake her ramification in her bed when she lies down to sleep .
She ’s that woman who is standing at the back of the movie theater of operations to catch a movie , because she ca n’t bear to sit still for two hours .
Woman wearing high heels. Generic.
Butterfield has severerestless peg syndrome .
The Peoria , Ariz. , house physician and retired nurse has had the sensory motor neurologic abnormality since childhood , but it ’s been especially bad for the last 15 years . When Butterfield sits still , she said it feels like a pressure builds in her articulatio genus joints that ca n’t be relieve unless she moves her legs .
" It sounds simple or blasé , but when you get the symptoms , it ’s so aggravating and so irritating especially if you ’re in a theatre or at lunch or dinner party and you have to get up , " Butterfield told MyHealthNewsDaily . " It impact your whole life . "
Butterfield takes one of the two medication approve by the Food and Drug Administration ( FDA ) for unsatisfied legs syndrome , but she has cycled through several drugs over the year because they tend to turn back being effective .
But now , she has a thirddrugoption to explore , because the FDA this week approved the drug Horizant for treat the disorder .
About the drug
Horizant , which is manufactured by GlaxoSmithKline and XenoPort Inc. , is recommended for once - day-by-day use for mass with moderate to severe restless stage syndrome . It was shown to be effective in two 12 - week clinical test , where patients on the drug had their symptom measured with an accusative exfoliation , and then compared with those taking a placebo , according to the FDA .
The drug contains gabapentin enacarbil , a molecule that is similar to one in drugs that treat seizure in people withepilepsy , enunciate Dr. Richard K. Bogan , who is one of the clinical investigators of the drug and president and aesculapian conductor of SleepMed Inc. of South Carolina , a caller that offer up symptomatic services and therapy gadget for eternal rest patients .
Horizant is an lengthy release drug , which means it ’s designed to be absorbed slowly throughout the nighttime so that it has a tenacious continuance of activeness , Bogan enjoin . It was designed to be absorb this way because restless legs syndrome symptoms incline to be bad in theevening hours , he said .
" It has a duration of action that treat when the patient has the circadian [ meter - related ] symptom , " Bogan told MyHealthNewsDaily .
However , people who tend to sleep during the day and are awake at Nox are counsel against taking the drug , according to the FDA .
A look at the syndrome
Scientists do n’t yet do it the accurate causal agent of restless branch syndrome , though the disorder tends to be transmissible , agree to the National Institutes of Health . In Butterfield ’s case , her father and brother also have the disorder .
Researchers also think that humble atomic number 26 levels in the psyche could put up to the syndrome , harmonize to the NIH .
Up to 10 per centum of people in the United States have some form of uneasy legs syndrome , and 2 percent to 3 pct have moderate to severe version of the syndrome , fit in to the NIH . Some cases are mild , involving thin soreness , while others are severe and can be atrocious .
Even though the novel drug ca n’t heal the disorder , " have a new medicament on the mart is going to give us another option , and we necessitate that option , " Butterfield said .
Pass it on : The FDA approved this week a new drug for treating restless ramification syndrome .
This report was provided byMyHealthNewsDaily , a sister site to LiveScience .
